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Selumetinib sulfate

Selumetinib sulfate (AZD6244 sulfate) is a potent, selective, and orally bioavailable MEK1/2 inhibitor. It is used in preclinical and clinical research for neurofibromatosis type 1, particularly for studying symptomatic, inoperable plexiform neurofibromas, based on in vitro and in vivo evidence.

Product Specifications

CAS Number

943332-08-9

Product Name Alternative

ARRY-142886 sulfate, AZD6244 sulfate

Field of Research

Cell Biology, Pharmacology & Drug Discovery, Signal Transduction

Purity

99.65% (May vary between batches)

Solubility

DMSO:40 mg/mL (71.97 mM) ; H2O:< 1 mg/mL (insoluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.6 mM)

Smiles

O=C (NOCCO) C1=CC2=C (N=CN2C) C (F) =C1NC3=CC=C (Br) C=C3Cl.O=S (=O) (O) O

Molecular Formula

C17H17BrClFN4O7S

Molecular Weight

555.76

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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