Cilengitide TFA
Cilengitide is a potent and selective cyclic RGD pentapeptide inhibitor of αvβ3 and αvβ5 integrins, with IC50 values of 4.1 nM and 79 nM, respectively. It has been widely used in preclinical in vitro and in vivo research to study angiogenesis, tumor growth, and metastasis in various cancer models.
Product Specifications
CAS Number
199807-35-7
Field of Research
Cell Biology, Immunology & Inflammation, Signal Transduction
Purity
99.72% (May vary between batches)
Smiles
OC (=O) C (F) (F) F.CC (C) [C@@H]1N (C) C (=O) [C@@H] (Cc2ccccc2) NC (=O) [C@H] (CC (O) =O) NC (=O) CNC (=O) [C@H] (CCCNC (N) =N) NC1=O
Molecular Formula
C29H41F3N8O9
Molecular Weight
702.68
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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