5- (Methoxycarbonyl) methyluridine
5- (Methoxycarbonyl) methyluridine (mcm5U) is a critical tRNA modification found in yeast that ensures proper anticodon loop structure for mRNA codon binding. Its absence, such as in Elongator complex mutants like elp3, is linked to translational defects and increased protein aggregation, making it a key molecule for studying translation fidelity and proteostasis in vivo.
Product Specifications
CAS Number
29428-50-0
Product Name Alternative
5-Methoxycarbonyl methyl uridine, 5- (Methoxycarbonyl) methyluridine (MCM5U)
Field of Research
Cell Biology, Molecular Biology
Purity
99.71% (May vary between batches)
Smiles
O[C@H]1[C@@H] (O[C@H] (CO) [C@H]1O) N2C (=O) NC (=O) C (CC (OC) =O) =C2
Molecular Formula
C12H16N2O8
Molecular Weight
316.26
Storage Conditions
Keep away from moisture, store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Notes
For research use only.
Available Sizes
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