GSK-1520489A
GSK-1520489A is a PKMYT1 (active protein kinase) inhibitor (IC50=115 nM, Ki=10.94 nM) [1].
Product Specifications
CAS Number
[1042433-41-9]
UNSPSC
12352005
Target
Wee1
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/gsk-1520489a.html
Purity
99.83
Solubility
DMSO : 35.71 mg/mL (ultrasonic; warming; heat to 70°C)
Smiles
O=C(C1=C(NC2=NC(NC3=CC=CC(CS(=O)(C)=O)=C3)=NC=C2C)C=CC=C1)NC
Molecular Formula
C21H23N5O3S
Molecular Weight
425.50
References & Citations
[1]Charlott Platzer, et al. Identification of PKMYT1 inhibitors by screening the GSK published protein kinase inhibitor set I and II. Bioorg Med Chem. 2018 Aug 7;26 (14) :4014-4024.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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