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5'-DMT-2'-O-TBDMS-N1-Methyl-PseudoUridine-CE-Phosphoramidite

This phosphoramidite derivative, CAS 875302-45-7, is a key building block for the solid-phase synthesis of oligonucleotides. It is primarily used in research to incorporate N1-methylpseudouridine modifications into RNA, enhancing stability and reducing immunogenicity for applications in mRNA therapeutics and in vitro transcript studies.

Product Specifications

CAS Number

875302-45-7

Field of Research

Cell Biology, Molecular Biology, Musculoskeletal & Connective Tissue Research

Smiles

C (OC[C@@H]1[C@@H] (OP (N (C (C) C) C (C) C) OCCC#N) [C@@H] (O[Si] (C (C) (C) C) (C) C) [C@@H] (O1) C=2C (=O) NC (=O) N (C) C2) (C3=CC=C (OC) C=C3) (C4=CC=C (OC) C=C4) C5=CC=CC=C5

Molecular Formula

C46H63N4O9PSi

Molecular Weight

875.07

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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