5'-O- (4,4'-Dimethoxytrityl) -2'-O- (2-methoxyethyl) -5-methyluridine
This 2'-O-MOE modified, 5-methyluridine derivative features a DMT-protected 5'-hydroxyl and an open 3'-OH, making it a key phosphoramidite precursor for synthesizing antisense oligonucleotides. Such oligonucleotides are widely used in vitro and in vivo for therapeutic target validation and gene silencing studies.
Product Specifications
CAS Number
163759-50-0
Field of Research
Cell Biology, Molecular Biology
Smiles
C (OC[C@H]1O[C@H] ([C@H] (OCCOC) [C@@H]1O) N2C (=O) NC (=O) C (C) =C2) (C3=CC=C (OC) C=C3) (C4=CC=C (OC) C=C4) C5=CC=CC=C5
Molecular Formula
C34H38N2O9
Molecular Weight
618.67
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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