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5'-O- (4,4'-Dimethoxytrityl) -2'-O- (2-methoxyethyl) -5-methyluridine

This 2'-O-MOE modified, 5-methyluridine derivative features a DMT-protected 5'-hydroxyl and an open 3'-OH, making it a key phosphoramidite precursor for synthesizing antisense oligonucleotides. Such oligonucleotides are widely used in vitro and in vivo for therapeutic target validation and gene silencing studies.

Product Specifications

CAS Number

163759-50-0

Field of Research

Cell Biology, Molecular Biology

Smiles

C (OC[C@H]1O[C@H] ([C@H] (OCCOC) [C@@H]1O) N2C (=O) NC (=O) C (C) =C2) (C3=CC=C (OC) C=C3) (C4=CC=C (OC) C=C4) C5=CC=CC=C5

Molecular Formula

C34H38N2O9

Molecular Weight

618.67

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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