3'-O-tert-Butyldimethylsilyl-5'-O-DMT-2'-deoxyadenosine

This is a protected 2'-deoxyadenosine derivative, featuring a tert-butyldimethylsilyl (TBDMS) group at the 3'-O position and a dimethoxytrityl (DMT) group at the 5'-O position, while the amino and 3'-OH groups remain available for further reaction. It serves as a key synthetic intermediate in oligonucleotide chemistry, specifically for solid-phase synthesis of DNA and antisense oligonucleotides for in vitro and in vivo research applications.