3'-O- (t-Butyldimethylsilyl) -2'-deoxyadenosine

This is a 2'-deoxyadenosine derivative with a 3'-O-TBDMS protecting group, leaving the amino and 5'-hydroxyl functionalities available for further modification. It serves as a key synthetic intermediate in oligonucleotide chemistry, particularly in the solid-phase synthesis of DNA and antisense oligonucleotides for in vitro and in vivo research applications.