2'-Fluoro-2'-deoxy-ara-C (Bz) -3'-phosphoramidite
This compound is a 2'-fluoro-modified arabinonucleoside phosphoramidite, specifically a benzoyl-protected derivative of cytidine. It serves as a critical building block for the solid-phase synthesis of oligonucleotides containing fluoro-arabino modifications, which are utilized in antisense and therapeutic aptamer research both in vitro and in vivo to enhance nuclease resistance and binding affinity.
Product Specifications
CAS Number
1404463-12-2
Field of Research
Cell Biology, Molecular Biology
Smiles
C (OC[C@@H]1[C@@H] (OP (N (C (C) C) C (C) C) OCCC#N) [C@H] (F) [C@@H] (O1) N2C (=O) N=C (NC (=O) C3=CC=CC=C3) C=C2) (C4=CC=C (OC) C=C4) (C5=CC=C (OC) C=C5) C6=CC=CC=C6
Molecular Formula
C46H51FN5O8P
Molecular Weight
851.9
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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