2'-Fluoro-2'-deoxy-ara-C (Bz) -3'-phosphoramidite

This compound is a 2'-fluoro-modified arabinonucleoside phosphoramidite, specifically a benzoyl-protected derivative of cytidine. It serves as a critical building block for the solid-phase synthesis of oligonucleotides containing fluoro-arabino modifications, which are utilized in antisense and therapeutic aptamer research both in vitro and in vivo to enhance nuclease resistance and binding affinity.