3'-O- (t-Butyldimethylsilyl) -2'-O- (2-methoxyethyl) uridine
This compound is a 2'-O- (2-methoxyethyl) modified uridine nucleoside derivative, featuring a 3'-O-TBDMS protecting group while leaving the amino and 5'-hydroxyl functions open. Such 2'-MOE modifications are widely utilized in the synthesis of antisense oligonucleotides for in vitro and in vivo research, enhancing nuclease resistance and target affinity.
Product Specifications
CAS Number
1345716-52-0
Field of Research
Cell Biology, Molecular Biology
Smiles
O (CCOC) [C@H]1[C@@H] (O[C@H] (CO) [C@H]1O[Si] (C (C) (C) C) (C) C) N2C (=O) NC (=O) C=C2
Molecular Formula
C18H32N2O7Si
Molecular Weight
416.54
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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