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3'-O- (t-Butyldimethylsilyl) -2'-O- (2-methoxyethyl) uridine

This compound is a 2'-O- (2-methoxyethyl) modified uridine nucleoside derivative, featuring a 3'-O-TBDMS protecting group while leaving the amino and 5'-hydroxyl functions open. Such 2'-MOE modifications are widely utilized in the synthesis of antisense oligonucleotides for in vitro and in vivo research, enhancing nuclease resistance and target affinity.

Product Specifications

CAS Number

1345716-52-0

Field of Research

Cell Biology, Molecular Biology

Smiles

O (CCOC) [C@H]1[C@@H] (O[C@H] (CO) [C@H]1O[Si] (C (C) (C) C) (C) C) N2C (=O) NC (=O) C=C2

Molecular Formula

C18H32N2O7Si

Molecular Weight

416.54

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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