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3'-O- (t-Butyldimethylsilyl) -2'-O- (2-methoxyethyl) -5-methyluridine

This is a 2'-O-methoxyethyl (2'-MOE) modified, 3'-O-TBDMS protected derivative of 5-methyluridine. It serves as a key synthetic intermediate in oligonucleotide chemistry, particularly for antisense research, where 2'-MOE modifications enhance nuclease resistance and binding affinity in vitro and in vivo.

Product Specifications

CAS Number

1221967-92-5

Smiles

O (CCOC) [C@H]1[C@@H] (O[C@H] (CO) [C@H]1O[Si] (C (C) (C) C) (C) C) N2C (=O) NC (=O) C (C) =C2

Molecular Formula

C19H34N2O7Si

Molecular Weight

430.57

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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