5'-O-TBDPS-2,2'-anhydrouridine

This protected nucleoside derivative, featuring a TBDPS group at the 5'-O position and a 2,2'-anhydro bridge, is a key synthetic intermediate. It is utilized in oligonucleotide synthesis and medicinal chemistry research for developing modified RNA analogs, with applications in both in vitro biochemical studies and in vivo therapeutic investigations.