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AMP-PCP disodium

AMP-PCP disodium is a non-hydrolyzable ATP analog that binds the N-terminal domain of Hsp90 with a Kd of 3.8 μM, promoting its active homodimeric state. This compound is used in vitro to study Hsp90's ATPase-driven chaperone cycle, conformational dynamics, and its role in protein folding and client protein stabilization.

Product Specifications

CAS Number

7414-56-4

Product Name Alternative

AMP PCP disodium, AMP-PCP, AMPPCP disodium, AMP-PCP disodium, HSP90

Field of Research

Metabolism Research, Signal Transduction

Purity

99.32% (May vary between batches)

Solubility

H2O:125 mg/mL (227.62 mM)

Smiles

O[C@H]1[C@@H] (O[C@@H] ([C@H]1O) COP (OP (CP ([O-]) ([O-]) =O) (O) =O) (O) =O) N2C3=NC=NC (N) =C3N=C2.[Na+].[Na+]

Molecular Formula

C11H16N5Na2O12P3

Molecular Weight

549.17

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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