PF-03463275
PF-03463275 is a potent, brain-penetrant, and selective reversible inhibitor of the glycine transporter 1 (GlyT1) with a Ki of 11.6 nM. It is utilized in neuroscience research to investigate the modulation of NMDA receptor function and has been studied in preclinical models for its potential to address cognitive impairments in schizophrenia.
Product Specifications
CAS Number
1173239-39-8
Product Name Alternative
GlyT1, PF 03463275, PF 3463275, PF03463275, PF-03463275, PF-3463275, PF3463275
Field of Research
Neuroscience
Purity
99.86% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween-80+45% Saline:1 mg/mL (2.65 mM) ; DMSO:30 mg/mL (79.61 mM)
Smiles
[H][C@@]12CN (C) C[C@]1 ([H]) [C@H]2CN (Cc1ccc (F) c (Cl) c1) C (=O) c1cn (C) cn1
Molecular Formula
C19H22ClFN4O
Molecular Weight
376.86
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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