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GSK-3 inhibitor 4

GSK-3 inhibitor 4 is an orally bioavailable, brain-penetrant small molecule that potently inhibits GSK-3α/β and CDK2/5 kinases. It effectively reduces Tau protein levels in cellular models, making it a useful research tool for investigating Alzheimer's disease pathology and related tauopathies.

Product Specifications

CAS Number

2227279-83-4

Product Name Alternative

CDK2, CDK5, GSK-3 inhibitor 4, GSK3inhibitor4, GSK3, GSK-3

Field of Research

Cell Biology, Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology

Purity

98.77% (May vary between batches)

Solubility

DMSO:50 mg/mL (123.95 mM)

Smiles

N (C (=O) C1=NC (NC2=CC=C (F) C=C2) =NC=C1) C=3C (=CC=NC3) C4=CC=C (F) C=C4

Molecular Formula

C22H15F2N5O

Molecular Weight

403.38

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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