GSK-3 inhibitor 4
GSK-3 inhibitor 4 is an orally bioavailable, brain-penetrant small molecule that potently inhibits GSK-3α/β and CDK2/5 kinases. It effectively reduces Tau protein levels in cellular models, making it a useful research tool for investigating Alzheimer's disease pathology and related tauopathies.
Product Specifications
CAS Number
2227279-83-4
Product Name Alternative
CDK2, CDK5, GSK-3 inhibitor 4, GSK3inhibitor4, GSK3, GSK-3
Field of Research
Cell Biology, Pharmacology & Drug Discovery, Signal Transduction, Stem Cell & Developmental Biology
Purity
98.77% (May vary between batches)
Solubility
DMSO:50 mg/mL (123.95 mM)
Smiles
N (C (=O) C1=NC (NC2=CC=C (F) C=C2) =NC=C1) C=3C (=CC=NC3) C4=CC=C (F) C=C4
Molecular Formula
C22H15F2N5O
Molecular Weight
403.38
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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