FL118
FL118 is a novel camptothecin analog that acts as a survivin inhibitor, suppressing cancer stem cell-like properties. It inhibits epithelial-mesenchymal transition, migration, and invasion in breast cancer cells by targeting the Wnt/β-catenin pathway, as demonstrated in in vitro studies.
Product Specifications
CAS Number
135415-73-5
Product Name Alternative
10,11- (Methylenedioxy) -20 (S) -camptothecin, 10,11- (Methylenedioxy) -20camptothecin, FL 118, FL118, FL-118, Survivin
Field of Research
Cell Biology
Purity
97.14% (May vary between batches)
Solubility
DMSO:2 mg/mL (5.1 mM)
Smiles
C (C) [C@]1 (O) C2=C (C (=O) N3C (=C2) C=4C (C3) =CC=5C (N4) =CC6=C (C5) OCO6) COC1=O
Molecular Formula
C21H16N2O6
Molecular Weight
392.36
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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