Clinofibrate
Clinofibrate (S-8527) is a hypelipidemic agent and a HMG-CoA reductase inhibitor.
Product Specifications
CAS Number
30299-08-2
Product Name Alternative
S-8527
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Autophagy; HMG-CoA Reductase (HMGCR)
Type
Reference compound
Related Pathways
Autophagy; Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/Clinofibrate.html
Concentration
10mM
Purity
98.54
Solubility
DMSO : 100 mg/mL (ultrasonic; warming; heat to 80°C)
Smiles
CCC(OC1=CC=C(C2(C3=CC=C(OC(CC)(C)C(O)=O)C=C3)CCCCC2)C=C1)(C)C(O)=O
Molecular Formula
C28H36O6
Molecular Weight
468.58
Precautions
H302, H315, H319, H335
References & Citations
[1]Okazaki M, et al. Effects of clinofibrate on plasma fibrinogen level in high fructose diet-induced hyperlipidemic rats. In Vivo. 1994 Nov-Dec;8 (6) :1057-61.|[2]Shirai K, et al. Effect of clinofibrate on lipid metabolism of aorta in atherosclerotic rats. Artery. 1983;12 (3) :145-55.|[3]Suzuki K, et al. Effects of S-8527 (1,1-bis4'- (1"-carboxy'1"-methylpropoxy) -phenyl) -cyclohexane), a new hypolipidemic compound, on triglyceride metablolism in rats. Biochem Pharmacol. 1975 Jun 15;24 (11-12) :1203-7.|[4]Suzuki K, et al. Hypolipidemic effect of a new aryloxy compound, S-8527, in experimental animals. Jpn J Pharmacol. 1974 Jun;24 (3) :407-14.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC040158-500 1x 500 µL
Cytokeratin 17 (E3), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC882216-100 1x 100 µL
CD50 / ICAM3 (CG106), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC880630-100 1x 100 µL
Mucin 1 / EMA / Episialin / CD227 (VU-2G7), CF488A conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC040050-100 1x 100 µL
IgA Secretory Component (SC05), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details