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Icopezil

Icopezil is a small molecule acetylcholinesterase (AChE) inhibitor used in neuroscience research. It serves as a tool compound for investigating cholinergic function in models of Alzheimer's disease and other neurological disorders, applicable in both in vitro enzymatic assays and in vivo behavioral studies.

Product Specifications

CAS Number

145508-78-7

Product Name Alternative

AChE

Field of Research

Neuroscience

Purity

98.16% (May vary between batches)

Solubility

DMSO:50 mg/mL (133.17 mM)

Smiles

C (CC1CCN (CC2=CC=CC=C2) CC1) C=3C4=C (C=C5C (=C4) CC (=O) N5) ON3

Molecular Formula

C23H25N3O2

Molecular Weight

375.46

References & Citations

Ye Bin Shin 1, Jin Hwan Kim 1, Min Kyeong Kwon 1, Jin Hyuk Myung 1, Dong Geon Lee 1, Sung Giu Jin 2, Myung Joo Kang 1, Yong Seok Choi Optimized method development and validation for determining donepezil in rat plasma: A liquid-liquid extraction, LC-MS/MS, and design of experiments approach PLoS One, (2024), Min Young Jeong et al. Coupling syringe system comprising drug nanosuspension and photo-crosslinked gelatin methacryloyl hydrogel for subcutaneous delivery with decreased initial exposure Materials & Design, (2025)

Pubmed id

39240870

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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