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Naluzotan hydrochloride

Naluzotan hydrochloride (PRX 00023 hydrochloride) is a potent and selective 5-HT1A receptor agonist (Ki ~5.1 nM) and a hERG K+ channel blocker (IC50 3800 nM) . It is a research compound used in preclinical studies investigating anxiety and depression, including in vitro receptor binding assays and in vivo behavioral models.

Product Specifications

CAS Number

740873-82-9

Product Name Alternative

5HT Receptor, 5HTReceptor, 5-HT1A, Naluzotan Hydrochloride, hERG Potassium Channel, PRX00023 Hydrochloride, PRX-00023 Hydrochloride, PRX 00023 hydrochloride, PRX 00023 Hydrochloride

Field of Research

Cardiovascular Research, Neuroscience, Pharmacology & Drug Discovery, Signal Transduction

Purity

98.61% (May vary between batches)

Solubility

DMSO:50 mg/mL (102.65 mM)

Smiles

Cl.O=C (NC1=CC=CC (=C1) N2CCN (CC2) CCCCNS (=O) (=O) CC3CCCCC3) C

Molecular Formula

C23H39ClN4O3S

Molecular Weight

487.1

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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