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CIA-1 (Free base)

CIA-1 (Free base) is a small molecule inhibitor of the nuclear receptor COUP-TFII, demonstrating in vitro activity with IC50 values of 1.2-7.6 μM in prostate cancer cells. It has also shown efficacy in inhibiting tumor growth in mouse xenograft models, supporting its use in oncology research for studying hormone-related cancers.

Product Specifications

CAS Number

452087-38-6

Product Name Alternative

COUP-TFII, CIA 1, CIA1, CIA-1, CIA-1 (Free base), CIA-1 (Free base), Gamma-secretase, Gammasecretase

Field of Research

Neuroscience, Pharmacology & Drug Discovery, Protein Biochemistry, Stem Cell & Developmental Biology

Purity

99.00% (May vary between batches)

Solubility

DMSO:60 mg/mL (182.14 mM)

Smiles

N (CCC1=CC (OC) =C (OC) C=C1) C2=C3C (SC (C) =C3) =NC=N2

Molecular Formula

C17H19N3O2S

Molecular Weight

329.42

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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