VU6036720
VU6036720 is a potent and selective small-molecule inhibitor of the Kir4.1/5.1 potassium channel heteromer. It suppresses channel activity by reducing both open probability and single-channel current amplitude. This compound is a valuable research tool for investigating the role of Kir4.1/5.1 in glial function, renal potassium handling, and related in vitro and in vivo disease models.
Product Specifications
Product Name Alternative
PotassiumChannel, Potassium Channel, Kir4.1, Kir5.1
Field of Research
Pharmacology & Drug Discovery
Purity
97.81% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:10 mg/mL (22.89 mM) ; DMSO:45 mg/mL (102.99 mM)
Smiles
N#CC1=CC=CC=C1N2C[C@H] (C) N (CCNS (=O) (C3=CC=C (F) C (Cl) =C3) =O) CC2
Molecular Formula
C20H22ClFN4O2S
Molecular Weight
436.93
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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