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PDS-0330

PDS-0330 is a micromolar-affinity, small-molecule inhibitor that binds directly and specifically to claudin-1. It disrupts the claudin-1/Src association, inhibiting colorectal cancer (CRC) progression and metastasis in research models, and exhibits chemosensitizing activity with characterized pharmacokinetics.

Product Specifications

CAS Number

2904682-19-3

Product Name Alternative

PDS 0330, PDS0330, PDS-0330, Claudin-1

Field of Research

Signal Transduction

Purity

98.81% (May vary between batches)

Solubility

DMSO:1 mg/mL (2.36 mM)

Smiles

N (C (NC (=O) C1=CC2=C (C=C1) C=CC=C2) =S) C3=CC=C (C4=NC=5C (O4) =CC=CC5) C=C3

Molecular Formula

C25H17N3O2S

Molecular Weight

423.49

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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