AB21 HCl
AB21 HCl is a potent and selective σ1 receptor antagonist, exhibiting a Ki of 13 nM for σ1 versus 102 nM for σ2. It is utilized in neuroscience research to study neuropathic pain mechanisms, as it has demonstrated efficacy in reducing mechanical hypersensitivity in validated in vivo models.
Product Specifications
Product Name Alternative
AB21 HCl, AB21HCL, Sigmareceptor, Sigma receptor, σ1, σ2
Field of Research
Pharmacology & Drug Discovery
Purity
99.89% (May vary between batches)
Solubility
DMSO:6.25 mg/mL (16.27 mM)
Smiles
O=C (N1CCC2 (CN (C2) CCC3=CC=CC=C3) CC1) CC4=CC=CC=C4.Cl
Molecular Formula
C23H29ClN2O
Molecular Weight
384.2
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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