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AB21 HCl

AB21 HCl is a potent and selective σ1 receptor antagonist, exhibiting a Ki of 13 nM for σ1 versus 102 nM for σ2. It is utilized in neuroscience research to study neuropathic pain mechanisms, as it has demonstrated efficacy in reducing mechanical hypersensitivity in validated in vivo models.

Product Specifications

Product Name Alternative

AB21 HCl, AB21HCL, Sigmareceptor, Sigma receptor, σ1, σ2

Field of Research

Pharmacology & Drug Discovery

Purity

99.89% (May vary between batches)

Solubility

DMSO:6.25 mg/mL (16.27 mM)

Smiles

O=C (N1CCC2 (CN (C2) CCC3=CC=CC=C3) CC1) CC4=CC=CC=C4.Cl

Molecular Formula

C23H29ClN2O

Molecular Weight

384.2

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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