6,7-dimethylisatin
6,7-Dimethylisatin is a small molecule inhibitor of the human GABA transporters hGAT3 (IC50 = 108 μM), hBGT1, and hGAT2. This compound serves as a useful pharmacological tool for in vitro studies investigating GABAergic neurotransmission and the roles of specific transporter subtypes in the central nervous system.
Product Specifications
CAS Number
20205-43-0
Product Name Alternative
6,7-dimethyl-1H-indole-2,3-dione, 6,7-dimethylisatin, GABA Receptor, GABAReceptor, GAT-3, GAT-1, GAT-2
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
98.98% (May vary between batches)
Solubility
DMSO:50 mg/mL (285.42 mM)
Smiles
CC1=C (C) C2=C (C=C1) C (=O) C (=O) N2
Molecular Formula
C10H9NO2
Molecular Weight
175.18
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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