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6,7-dimethylisatin

6,7-Dimethylisatin is a small molecule inhibitor of the human GABA transporters hGAT3 (IC50 = 108 μM), hBGT1, and hGAT2. This compound serves as a useful pharmacological tool for in vitro studies investigating GABAergic neurotransmission and the roles of specific transporter subtypes in the central nervous system.

Product Specifications

CAS Number

20205-43-0

Product Name Alternative

6,7-dimethyl-1H-indole-2,3-dione, 6,7-dimethylisatin, GABA Receptor, GABAReceptor, GAT-3, GAT-1, GAT-2

Field of Research

Neuroscience, Pharmacology & Drug Discovery

Purity

98.98% (May vary between batches)

Solubility

DMSO:50 mg/mL (285.42 mM)

Smiles

CC1=C (C) C2=C (C=C1) C (=O) C (=O) N2

Molecular Formula

C10H9NO2

Molecular Weight

175.18

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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