IK-930
IK-930 is a potent, orally bioavailable small molecule inhibitor of the TEAD transcription factors, exhibiting sub-micromolar activity (EC50 < 0.1 μM) . It is a valuable research tool for investigating the Hippo signaling pathway in cancer research, with utility in both in vitro cellular assays and in vivo preclinical models.
Product Specifications
CAS Number
2563892-44-2
Product Name Alternative
Compound I-32, IK 930, IK930, IK-930, YAP–TEAD
Field of Research
Stem Cell & Developmental Biology
Purity
98.86% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.77 mM) ; DMSO:117.5 mg/mL (276.84 mM)
Smiles
N (CC1=CC=C (C (F) (F) F) C=C1) C2=C (C=C (S (NC) (=O) =O) C=C2) C=3N=CN (C) C3
Molecular Formula
C19H19F3N4O2S
Molecular Weight
424.44
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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