FD274
FD274 is a potent dual PI3K/mTOR inhibitor active against PI3Kα/β/γ/δ and mTOR. It demonstrates significant in vitro antiproliferative activity in AML cell lines and exhibits dose-dependent in vivo antitumor efficacy in HL-60 xenograft models, supporting its research use in acute myeloid leukemia.
Product Specifications
CAS Number
2641899-38-7
Field of Research
Signal Transduction
Smiles
O=S (=O) (NC=1C=C (C=NC1Cl) C2=CN=C3NN=C (C=4C=CN=CC4) C3=C2) C5=CC=C (F) C=C5
Molecular Formula
C22H14ClFN6O2S
Molecular Weight
480.9
Storage Conditions
-20°C
Notes
For research use only.
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