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FD274

FD274 is a potent dual PI3K/mTOR inhibitor active against PI3Kα/β/γ/δ and mTOR. It demonstrates significant in vitro antiproliferative activity in AML cell lines and exhibits dose-dependent in vivo antitumor efficacy in HL-60 xenograft models, supporting its research use in acute myeloid leukemia.

Product Specifications

CAS Number

2641899-38-7

Field of Research

Signal Transduction

Smiles

O=S (=O) (NC=1C=C (C=NC1Cl) C2=CN=C3NN=C (C=4C=CN=CC4) C3=C2) C5=CC=C (F) C=C5

Molecular Formula

C22H14ClFN6O2S

Molecular Weight

480.9

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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