TCO-PEG4-NHS ester
TCO-PEG4-NHS ester is a polyethylene glycol-based linker featuring a cleavable trans-cyclooctene group and an NHS ester for amine conjugation. It is widely employed in chemical research for constructing PROTAC degraders and antibody-drug conjugates (ADCs), with applications in both in vitro and in vivo experimental settings.
Product Specifications
CAS Number
1613439-69-2
Product Name Alternative
Cleavable, ADC Linker, ADCLinker, TCO PEG4 NHS ester, TCOPEG4NHS ester, TCO-PEG-4-NHS ester, TCO-PEG4-NHS ester, PROTAC
Field of Research
Pharmacology & Drug Discovery
Purity
99.35% (May vary between batches)
Solubility
DMSO:25.73 mg/mL (50 mM)
Smiles
O (C (CCOCCOCCOCCOCCNC (OC1CCCC=CCC1) =O) =O) N2C (=O) CCC2=O
Molecular Formula
C24H38N2O10
Molecular Weight
514.57
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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