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RGFP966 (E-isomer)

RGFP966 is a potent and highly selective HDAC3 inhibitor, demonstrating an IC50 of 0.08 μM and over 200-fold selectivity versus other HDAC isoforms. It is widely used in research to investigate epigenetic mechanisms in neurobiology, oncology, and metabolic diseases, with applications in both cellular and animal models.

Product Specifications

CAS Number

1396841-57-8

Product Name Alternative

RGFP 966, RGFP966, RGFP-966, E-isomer, HDAC3

Field of Research

Epigenetics & Chromatin, Molecular Biology

Purity

99.10% (May vary between batches)

Solubility

Ethanol:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.52 mM) ; DMSO:67 mg/mL (184.88 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble)

Smiles

Nc1cc (F) ccc1NC (=O) \C=C\c1cnn (CC=Cc2ccccc2) c1

Molecular Formula

C21H19FN4O

Molecular Weight

362.4

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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