RGFP966 (E-isomer)
RGFP966 is a potent and highly selective HDAC3 inhibitor, demonstrating an IC50 of 0.08 μM and over 200-fold selectivity versus other HDAC isoforms. It is widely used in research to investigate epigenetic mechanisms in neurobiology, oncology, and metabolic diseases, with applications in both cellular and animal models.
Product Specifications
CAS Number
1396841-57-8
Product Name Alternative
RGFP 966, RGFP966, RGFP-966, E-isomer, HDAC3
Field of Research
Epigenetics & Chromatin, Molecular Biology
Purity
99.10% (May vary between batches)
Solubility
Ethanol:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.52 mM) ; DMSO:67 mg/mL (184.88 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble)
Smiles
Nc1cc (F) ccc1NC (=O) \C=C\c1cnn (CC=Cc2ccccc2) c1
Molecular Formula
C21H19FN4O
Molecular Weight
362.4
Storage Conditions
-20°C
Notes
For research use only.
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