Xanthone
Xanthone is a monoamine oxidase A (MAO-A) inhibitor with an IC50 of 0.84 µM. Xanthon inhibits Norepinephrine and high-K+-induced vasoconstriction with IC50 values of 60.26 μM and 82.9 μM, respectively. Xanthon increases intracellular cyclic adenosine 3′,5′-monophosphate (cAMP) content and blocks Ca2+ channels. Xanthone is the scaffold of several pharmacologically active compounds[1][2].
Product Specifications
CAS Number
90-47-1
UNSPSC
12352005
Hazard Statement
H410
Target
Calcium Channel; Monoamine Oxidase
Type
Natural Products
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Cancer-programmed cell death
Field of Research
Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/xanthone.html
Concentration
10mM
Purity
99.97
Solubility
DMSO : 10 mg/mL (ultrasonic)
Smiles
O=C1C2=C(OC3=C1C=CC=C3)C=CC=C2
Molecular Formula
C13H8O2
Molecular Weight
196.21
Precautions
H410
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
Store at room temperature 3 years
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
MAO-A
Available Sizes
Frequently Asked Questions
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