What is the catalog number for Echistatin?

The catalog number for Echistatin is HY-P1189.

What sizes are available for Echistatin?

Echistatin is available in the following size(s): 1 mg, 5 mg.

How many pack sizes does Echistatin come in?

Echistatin is available in 2 different pack sizes.

Is Echistatin in stock?

Echistatin is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures Echistatin?

Echistatin is manufactured by QuantiMol.

What is the estimated delivery time for Echistatin?

Estimated delivery time for Echistatin is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for Echistatin?

The safety data sheet for Echistatin is available here: http://file.medchemexpress.com/batch_PDF/HY-P1189/Echistatin-SDS-MedChemExpress.pdf.

Echistatin

Echistatin, the smallest active RGD protein belonging to the family of disintegrins that are derived from snake venoms, is a potent inhibitor of platelet aggregation. Echistatin is a potent inhibitor of bone resorption in culture. Echistatin is a potent antagonist of αIIbβ3, αvβ3 and α5β1[1][2][3][4].

Product Specifications

CAS Number

154303-05-6

UNSPSC

12352209

Hazard Statement

H302+H312+H332

Target

Integrin

Type

Peptides

Related Pathways

Cytoskeleton

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/echistatin.html

Purity

91.33

Solubility

H2O

Smiles

O=C(N[C@@H](CSSC[C@@H](C(N[C@@H](CCCCN)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC(C)C)C(N[C@@H](CCCCN)C(N[C@@H](CCC(O)=O)C(NCC(N[C@@H]([C@H](O)C)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CSSC[C@@H](C(N2[C@@H](CCC2)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(N)=O)C(N3[C@@H](CCC3)C(N[C@@H](CC4=CNC=N4)C(N[C@@H](CCCCN)C(NCC(N5[C@@H](CCC5)C(N[C@@H](C)C(N[C@@H]([C@H](O)C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)NC6=O)C(N[C@@H](CCCCN)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C)C(N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H](CC(O)=O)C(N[C@@H](CC(O)=O)C(N[C@@H](CCSC)C(N[C@@H](CC(O)=O)C(N[C@@H](CC(O)=O)C(N[C@H]7CC8=CC=C(C=C8)O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)NC9=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CO)C(NCC(N%10[C@@H](CCC%10)C(N[C@@H](CSSC[C@@H](C(N[C@@H](CC(N)=O)C(NCC(N[C@@H](CCCCN)C(N[C@H]%11[C@H](O)C)=O)=O)=O)=O)NC7=O)C(N[C@@H](CSSC[C@@H](C(N[C@H]6CC(O)=O)=O)NC%11=O)C(N[C@@H](CCCNC(N)=N)C(N[C@H]9CC(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCC(O)=O)N

Molecular Formula

C217H341N71O74S9

Molecular Weight

5417.00

Precautions

H302+H312+H332

References & Citations

[1]J Musial, et al. Inhibition of platelet adhesion to surfaces of extracorporeal circuits by disintegrins. RGD-containing peptides from viper venoms. Circulation. 1990 Jul;82 (1) :261-73.|[2]M Sato, et al. Echistatin is a potent inhibitor of bone resorption in culture. J Cell Biol. 1990 Oct;111 (4) :1713-23.|[3]C C Kumar, et al. Biochemical characterization of the binding of echistatin to integrin alphavbeta3 receptor. J Pharmacol Exp Ther. 1997 Nov;283 (2) :843-53.|[4]I Wierzbicka-Patynowski, et al. Structural requirements of echistatin for the recognition of alpha (v) beta (3) and alpha (5) beta (1) integrins. J Biol Chem. 1999 Dec 31;274 (53) :37809-14.