EG01377 2HCl
EG01377 2HCl is a potent and selective neuropilin-1 (NRP1) inhibitor with a Kd of 1.32 μM and an IC50 of 609 nM. This small molecule exhibits anti-angiogenic and antimigratory properties, demonstrating antitumor efficacy in both cellular assays and in vivo models of cancer research.
Product Specifications
CAS Number
2749438-61-5
Product Name Alternative
Neuropilin-1 (NRP1), EG 01377, EG01377, EG-01377, EG01377 2HCl, EG01377 2HCl (2227996-00-9 Free base), Complement System, ComplementSystem
Field of Research
Immunology & Inflammation
Purity
98.91% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (7.58 mM) ; DMSO:180 mg/mL (272.89 mM)
Smiles
N=C (N) NCCC[C@@H] (C (O) =O) NC (C (SC=C1) =C1NS (=O) (C2=C3C (CCO3) =CC (C4=CC=C (C=C4) CN) =C2) =O) =O.Cl.Cl
Molecular Formula
C26H32Cl2N6O6S2
Molecular Weight
659.6
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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