BMS-1166-n-piperidine-co-n-piperazine dihydrochloride
BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride is a resorcinol-based small molecule PD-1/PD-L1 interaction inhibitor (IC50 = 39.2 nM) . This compound serves as a key building block for synthesizing PROTAC degraders targeting the PD-1/PD-L1 pathway, facilitating research in immuno-oncology for potential anticancer applications in vitro.
Product Specifications
CAS Number
2691796-83-3
Product Name Alternative
BMS-1166-N-piperidine-CO-N-piperazine, BMS1166NpiperidineCONpiperazinedihydrochloride, PD-1, PD1/PDL1, PD1, PD-1/PD-L1, PD-L1, PDL1
Field of Research
Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery
Purity
98.00% (May vary between batches)
Smiles
Cl.Cl.Cc1c (COc2cc (OCc3cccc (c3) C#N) c (CN3CCCCC3C (=O) N3CCNCC3) cc2Cl) cccc1-c1ccc2OCCOc2c1
Molecular Formula
C41H45Cl3N4O5
Molecular Weight
780.18
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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