EM-651
EM-651 is the (2R) -enantiomer of the pure antiestrogen EM-652, exhibiting an IC50 of 20.0 nM for estrogen receptor antagonism. This compound is a research tool for studying hormone-dependent cancers, such as breast cancer, in both cellular and animal models to investigate antiestrogen mechanisms and therapeutic potential.
Product Specifications
CAS Number
182167-58-4
Product Name Alternative
2H-1-Benzopyran-7-ol, 3- (4-hydroxyphenyl) -4-methyl-2-[4-[2- (1-piperidinyl) ethoxy]phenyl]-, (2R) -, EM 651, EM651, EM-651
Purity
99.27% (May vary between batches)
Solubility
DMSO:45 mg/mL (98.35 mM)
Smiles
CC1=C ([C@H] (OC=2C1=CC=C (O) C2) C3=CC=C (OCCN4CCCCC4) C=C3) C5=CC=C (O) C=C5
Molecular Formula
C29H31NO4
Molecular Weight
457.56
Storage Conditions
-20°C
Notes
For research use only.
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