UNC 1025
UNC1062 is a potent and highly selective MERTK tyrosine kinase inhibitor, with an IC50 of 1.1 nM. It demonstrates functional activity in vitro by inhibiting melanoma cell proliferation, colony formation, and invasion, and shows selectivity over related TAM family kinases TYRO3 and AXL.
Product Specifications
CAS Number
1350549-36-8
Product Name Alternative
UNC1025, UNC-1025, UNC 1025, MERTK
Field of Research
Signal Transduction
Purity
98.99% (May vary between batches)
Solubility
DMSO:55 mg/mL (106.87 mM)
Smiles
CCCCNc1ncc2c (nn ([C@H]3CC[C@H] (O) CC3) c2n1) -c1ccc (cc1) S (=O) (=O) N1CCOCC1
Molecular Formula
C25H34N6O4S
Molecular Weight
514.64
Storage Conditions
-20°C
Notes
For research use only.
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