Rel-TREM2 agonist-2
Rel-TREM2 agonist-2 is a potent small molecule agonist of the TREM2 receptor, exhibiting a half-maximal activity concentration (C50) of ≤0.05 μM and a maximal effect (E.max) exceeding 250 μM. This compound is a valuable research tool for investigating TREM2 signaling in vitro and exploring its therapeutic potential in neurodegenerative disease models such as Alzheimer's in vivo.
Product Specifications
CAS Number
2738485-99-7
Product Name Alternative
Rel5 (4Chloro2fluorophenyl) 2,3dimethyl7[ (2R,4S) tetrahydro2 (1methyl1Hpyrazol4yl) 2Hpyran4yl]pyrido[3,4b]pyrazine
Field of Research
Cancer Biology; Neuroscience; Pharmacology & Drug Discovery
Purity
99.00% (May vary between batches)
Solubility
DMSO:55 mg/mL (121.7 mM)
Smiles
CC1=NC=2C (=NC (=CC2N=C1C) [C@@H]3C[C@@H] (OCC3) C4=CN (C) N=C4) C5=C (F) C=C (Cl) C=C5
Molecular Formula
C24H23ClFN5O
Molecular Weight
451.92
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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