JI6
JI6 is a potent, selective, and orally bioavailable small molecule inhibitor primarily targeting FLT3 (IC50 ~40 nM WT), with additional activity against c-Kit and JAK3. It is a valuable research tool for studying acute myeloid leukemia, demonstrating efficacy in both cellular assays and in vivo models of FLT3-driven disease.
Product Specifications
CAS Number
856436-16-3
Product Name Alternative
JI 6, JI6, JI-6, JAK3 Inhibitor VI, FLT3
Field of Research
Cardiovascular Research, Epigenetics & Chromatin, Signal Transduction, Stem Cell & Developmental Biology
Purity
97.74% (May vary between batches)
Solubility
DMSO:4.5 mg/mL (11.74 mM)
Smiles
CS (=O) (O) =O.O=C (/C1=C\C2=CC=CN2) NC (C=C3) =C1C=C3C4=CN=CC=C4
Molecular Formula
C19H17N3O4S
Molecular Weight
383.42
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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