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MTOR inhibitor 9f

The compound 9f is a potent and selective mTOR inhibitor, exhibiting IC50 values of 1.25 nM for mTOR and 82 nM for PI3Kα. It serves as a valuable chemical probe for studying mTOR signaling in cancer research and has demonstrated utility in both cellular and in vivo models of tumor growth.

Product Specifications

CAS Number

1144075-42-2

Product Name Alternative

1 (4 (4 (8oxa3azabicyclo[3.2.1]octan3yl) thieno[3,2d]pyrimidin2yl) phenyl) 3phenylurea, mTOR inhibitor 9f, mTOR, PI3Kα

Field of Research

Pharmacology & Drug Discovery; Cell Biology, Signal Transduction

Purity

98.39% (May vary between batches)

Solubility

DMSO:45 mg/mL (98.35 mM)

Smiles

N (C (NC1=CC=CC=C1) =O) C2=CC=C (C3=NC (=C4C (=N3) C=CS4) N5CC6OC (C5) CC6) C=C2

Molecular Formula

C25H23N5O2S

Molecular Weight

457.55

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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