MTOR inhibitor 9f
The compound 9f is a potent and selective mTOR inhibitor, exhibiting IC50 values of 1.25 nM for mTOR and 82 nM for PI3Kα. It serves as a valuable chemical probe for studying mTOR signaling in cancer research and has demonstrated utility in both cellular and in vivo models of tumor growth.
Product Specifications
CAS Number
1144075-42-2
Product Name Alternative
1 (4 (4 (8oxa3azabicyclo[3.2.1]octan3yl) thieno[3,2d]pyrimidin2yl) phenyl) 3phenylurea, mTOR inhibitor 9f, mTOR, PI3Kα
Field of Research
Pharmacology & Drug Discovery; Cell Biology, Signal Transduction
Purity
98.39% (May vary between batches)
Solubility
DMSO:45 mg/mL (98.35 mM)
Smiles
N (C (NC1=CC=CC=C1) =O) C2=CC=C (C3=NC (=C4C (=N3) C=CS4) N5CC6OC (C5) CC6) C=C2
Molecular Formula
C25H23N5O2S
Molecular Weight
457.55
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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