MTOR inhibitor 9d
The small molecule mTOR inhibitor 9d is a potent dual inhibitor of mTOR and PI3K kinases, exhibiting an mTOR IC50 of 0.31 nM. It is utilized in cancer research, including studies on leukemia and solid tumors, with applications in both in vitro cellular assays and in vivo xenograft models.
Product Specifications
CAS Number
1144075-38-6
Product Name Alternative
MTOR, mTOR inhibitor 9d, 1 (2hydroxyethyl) 3{4[4 (8oxa3azabicyclo[3.2.1]oct3yl) thieno[3,2d]pyrimidin2yl]phenyl}urea, PI3K
Field of Research
Pharmacology & Drug Discovery; Cell Biology, Signal Transduction
Purity
98.90% (May vary between batches)
Solubility
DMSO:45 mg/mL (105.76 mM)
Smiles
N (C (NCCO) =O) C1=CC=C (C2=NC (=C3C (=N2) C=CS3) N4CC5OC (C4) CC5) C=C1
Molecular Formula
C21H23N5O3S
Molecular Weight
425.5
Storage Conditions
-20°C
Notes
For research use only.
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