MTOR inhibitor 9a
This compound, a potent mTOR inhibitor, exhibits an IC50 of 80 nM against human LNCaP prostate cancer cell growth in vitro. Its antitumor potential is supported by research into mTOR pathway biology and oncology, suggesting utility in both cellular and preclinical animal studies.
Product Specifications
CAS Number
1144075-32-0
Product Name Alternative
1methyl3{4[4 (8oxa3azabicyclo[3.2.1]oct3yl) thieno[3,2d]pyrimidin2yl]phenyl}urea, mTOR inhibitor 9a
Field of Research
Pharmacology & Drug Discovery; Cell Biology
Purity
99.75% (May vary between batches)
Solubility
DMSO:12 mg/mL (30.34 mM)
Smiles
N (C (NC) =O) C1=CC=C (C2=NC (=C3C (=N2) C=CS3) N4CC5OC (C4) CC5) C=C1
Molecular Formula
C20H21N5O2S
Molecular Weight
395.48
Storage Conditions
-20°C
Notes
For research use only.
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225116-01 50 µL
PLA2G2A (EC 3.1.1.4, GIIC sPLA2, Group IIA phospholipase A2, Group X secretory phospholipase A2 Precursor, GX sPLA2, GXPLA2, GXSPLA2, Membrane Associated, MOM1, Non-pancreatic secretory phospholipase A2, NPS-PLA2, OTTHUMP00000002786, PA2GA, Phosphatidylcholine 2-acylhydrolase 2A, Phosphatidylcholine 2-acylhydrolase GX, Phospholipase A2, Phospholipase A2 group IIA, Phospholipase A2 group X, Phospholipase A2, group IIA (platelets, synovial fluid), PLA2, PLA2B, PLA2G2A, PLA2L, PLA2S, PLAS1, RASF A, sP) discontinued
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PLA2G2A (EC 3.1.1.4, GIIC sPLA2, Group IIA phospholipase A2, Group X secretory phospholipase A2 Precursor, GX sPLA2, GXPLA2, GXSPLA2, Membrane Associated, MOM1, Non-pancreatic secretory phospholipase A2, NPS-PLA2, OTTHUMP00000002786, PA2GA, Phosphatidylcholine 2-acylhydrolase 2A, Phosphatidylcholine 2-acylhydrolase GX, Phospholipase A2, Phospholipase A2 group IIA, Phospholipase A2 group X, Phospholipase A2, group IIA (platelets, synovial fluid), PLA2, PLA2B, PLA2G2A, PLA2L, PLA2S, PLAS1, RASF A, sP) discontinued
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