MTOR inhibitor 9c
MTOR inhibitor 9c is a highly selective mTOR inhibitor, exhibiting potent activity against mTOR with an IC50 of 0.7 nM while showing significantly weaker inhibition of PI3Kα (IC50 = 825 nM) . This selectivity profile makes it a valuable chemical probe for studying mTOR-dependent signaling pathways in cancer research and cell biology, applicable in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
1144075-36-4
Product Name Alternative
1 (2fluoroethyl) 3{4[4 (8oxa3azabicyclo[3.2.1]oct3yl) thieno[3,2d]pyrimidin2yl]phenyl}urea, mTOR inhibitor 9c, mTOR, PI3Kα
Field of Research
Pharmacology & Drug Discovery; Cell Biology, Signal Transduction
Purity
98.73% (May vary between batches)
Solubility
DMSO:60 mg/mL (140.35 mM)
Smiles
N (C (NCCF) =O) C1=CC=C (C2=NC (=C3C (=N2) C=CS3) N4CC5OC (C4) CC5) C=C1
Molecular Formula
C21H22FN5O2S
Molecular Weight
427.5
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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