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MTOR inhibitor 9c

MTOR inhibitor 9c is a highly selective mTOR inhibitor, exhibiting potent activity against mTOR with an IC50 of 0.7 nM while showing significantly weaker inhibition of PI3Kα (IC50 = 825 nM) . This selectivity profile makes it a valuable chemical probe for studying mTOR-dependent signaling pathways in cancer research and cell biology, applicable in both in vitro and in vivo experimental models.

Product Specifications

CAS Number

1144075-36-4

Product Name Alternative

1 (2fluoroethyl) 3{4[4 (8oxa3azabicyclo[3.2.1]oct3yl) thieno[3,2d]pyrimidin2yl]phenyl}urea, mTOR inhibitor 9c, mTOR, PI3Kα

Field of Research

Pharmacology & Drug Discovery; Cell Biology, Signal Transduction

Purity

98.73% (May vary between batches)

Solubility

DMSO:60 mg/mL (140.35 mM)

Smiles

N (C (NCCF) =O) C1=CC=C (C2=NC (=C3C (=N2) C=CS3) N4CC5OC (C4) CC5) C=C1

Molecular Formula

C21H22FN5O2S

Molecular Weight

427.5

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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